Glycine

Merck Life Science Limited

Glycine

Code: SG7126-10MG

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Average lead time: 29-07-2026

Per: 10MG

€120.00 ex VAT

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Product Description

Chemical Identifiers
Linear Formula: NH2CH2COOH
CAS Number: 56-40-6
Molecular Weight: 75.07
EC Number: 200-272-2
MDL Number: MFCD00008131
Beilstein/REAXYS Number: 635782
PubChem Substance ID: 24895290
eCl@ss: 32160406
UNSPSC Code: 12352209
NACRES: NA.26
SMILES: NCC(O)=O
InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N

Properties
Product Line: ReagentPlus®
Assay: ≥99% (HPLC)
Form: powder
Color: white to off white
Technique: western blot (suitable)
Functional Group: amine, carboxylic acid
pKa (25 °C): (1) 2.35, (2) 9.60
Melting Point: 240 °C (dec.) (lit.)
Solubility: H2O: 200 mg/mL, clear, colorless to faintly yellow
Impurities: ≤0.01% Ammonia
Cation Traces: ≤0.01% (Ammonia, NH3)
Loss on Drying: ≤0.2%
Storage Temp: room temperature
Application: advanced drug delivery

Description
General Description: Glycine is a non chiral, proteinogenic amino acid with a pI of 6.7, similar to the pH of the stacking region in polyacrylamide gels. It offers low mobility, hydrophobicity, and does not associate with proteins. This non essential, non polar glucogenic amino acid acts as an inhibitory neurotransmitter in the central nervous system, and works alongside glutamate as a co agonist at NMDA receptors. As a precursor, it serves as a building block for various macromolecules.
Research Uses: Its zwitterionic nature makes it an effective buffer across a range of pH values, giving it a critical role in protein analysis techniques such as SDS PAGE, Western Blotting, chromatography, and cell culture. It is widely used in buffer preparation for immunology research, in enzymatic assays such as lactate determination, and in the formulation of buffers for protein stabilization and pH control.
Application: Added to the transfer buffer during western blotting. Used to dissolve formazan crystals in the MTT cytotoxicity assay, and to terminate the rat basophilic leukemia (RBL) assay.
Biochemical Actions: An inhibitory neurotransmitter in the spinal cord and central nervous system, acting as an allosteric regulator of NMDA (N-methyl-D-aspartate) receptors. It is involved in the processing of motor and sensory data, regulating movement, vision, and audition.
Features and Benefits: High quality compound suitable for cell biology, biochemical research, and multiple research applications.

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Glycine

Glycine

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